Purdue Center for Cancer Research begins using Tyler Trent's donated cells for research

The Purdue Center for Cancer Research has launched a new research program that uses Tyler Trent's cancer cells. Prior to his death on Jan. 1, Tyler donated his osteosarcoma tumors.

Posted: May 14, 2019 5:23 PM
Updated: May 15, 2019 11:32 PM

WEST LAFAYETTE, Ind. (WLFI) - The Purdue Center for Cancer Research has launched a new research program that uses Tyler Trent's cancer cells. Prior to his death on Jan. 1, Tyler donated his osteosarcoma tumors.

The initiative, announced Tuesday, is a collaborative effort between Dr. David Nolte and Dr. John Turek. The two will work together to develop a process that measures cell motion, according to the Purdue Center for Cancer Research. When cells in biop­sies or tissue collected during surgery is exposed to chemotherapy agents, active agents induce different cell motion than inactive agents. The process, called Biodynamic Imaging, will be used in along with doctors from Riley Children's Hospital to identify osteosarcoma chemo sensitivity. 

Although he's been in the field for many years, this process is different for researcher John Turek.

"We've looked at many many tissues from patients but never before have I known the name or actually anything about the patient," said Turek. 

Researchers will work to understand how Tyler's tissue responds to various drugs. Turek said that's important because genetic information isn't helpful in most pediatric cancers.

"It will actually allow us to link a lot of that information back to genetic information and other information that they have on these tumors and that will allow us to begin to design clinical trials and research that will benefit future patients."

Purdue Center For Cancer Research's Director Timothy Ratliff said research like this comes at an especially important time.

"We've got probably 11 drugs in clinical trials right now, some are in the last stage before FDA approval, we're making a whole lot more and with Tyler's help we're going to really discover some cures for that osteosarcoma."

Tyler was a student member of the Purdue Center For Cancer Research's Director's Advancement Board. Tyler died on New Year's Day after his battle with Osteosarcoma, a rare form of bone cancer. He captivated the hearts of the world for his positive spirit and platform to fight the disease.

The center also announced two other collaborative research initiatives to honor Tyler's legacy.

The Purdue Center for Cancer Research said Dr. Philip Low has developed new technology that allows Chimeric Antigen Receptor (CAR) T cells to be collected from the patient. Then, it can be modified and injected back so their own CAR T cells can target and destroy the cancer cells. This technology is set to go to trial this summer, according to PCCR. 

Dr. Nolte, Dr. Turek and Dr. Micheal Childress are also working with the Biodynamic Imaging to identify chemosensitivity in canine osteosarcoma. The disease is similar to the human version, so it can be tested with the same chemotherapeutic agents in which will help better define the model for future studies. Because of Purdue's Veterinary Clinic and teaching college, the PUCC canine oncology doctors are able work with canine cancers as they present in the clinic.

You can give to the Tyler Trent Research Endowment here. 

 

West Lafayette
Clear
55° wxIcon
Hi: 75° Lo: 46°
Feels Like: 55°
Kokomo
Clear
46° wxIcon
Hi: 72° Lo: 42°
Feels Like: 44°
Rensselaer
Clear
45° wxIcon
Hi: 73° Lo: 41°
Feels Like: 45°
Fowler
Clear
45° wxIcon
Hi: 72° Lo: 43°
Feels Like: 45°
Williamsport
Clear
49° wxIcon
Hi: 73° Lo: 43°
Feels Like: 47°
Crawfordsville
Clear
47° wxIcon
Hi: 74° Lo: 45°
Feels Like: 47°
Frankfort
Clear
55° wxIcon
Hi: 72° Lo: 43°
Feels Like: 55°
Delphi
Clear
50° wxIcon
Hi: 73° Lo: 43°
Feels Like: 50°
Monticello
Clear
50° wxIcon
Hi: 74° Lo: 43°
Feels Like: 50°
Logansport
Clear
45° wxIcon
Hi: 71° Lo: 42°
Feels Like: 41°
Clear, Warmer Start To The Work Week
WLFI Radar
WLFI Temps
WLFI Planner

Indiana Coronavirus Cases

Data is updated nightly.

Confirmed Cases: 110759

Reported Deaths: 3503
CountyConfirmedDeaths
Marion20645758
Lake10172317
Elkhart6321108
St. Joseph600797
Allen5921200
Hamilton4646109
Vanderburgh327129
Hendricks2638121
Monroe236836
Johnson2250122
Tippecanoe218413
Clark210156
Porter203344
Cass19279
Delaware184261
Vigo175722
Madison156575
LaPorte135637
Floyd130061
Howard127063
Kosciusko118717
Bartholomew114557
Warrick111935
Marshall98024
Boone94446
Dubois94018
Hancock90042
Noble87632
Grant86733
Henry75424
Wayne73714
Jackson7319
Morgan69438
Shelby66329
Daviess63927
LaGrange62911
Dearborn62128
Clinton59112
Harrison55624
Putnam5209
Montgomery50221
Lawrence50028
White47814
Knox4769
Gibson4644
Decatur45339
DeKalb44211
Miami4223
Fayette41713
Greene41535
Jasper3802
Steuben3647
Scott35310
Sullivan32812
Jennings30812
Posey2940
Franklin29325
Clay2925
Orange28224
Ripley2788
Carroll26913
Wabash2608
Washington2571
Starke2487
Wells2472
Whitley2476
Adams2403
Jefferson2403
Fulton2302
Huntington2173
Spencer2154
Tipton21522
Randolph2067
Perry20213
Newton17011
Jay1680
Owen1641
Martin1590
Rush1494
Pike1361
Vermillion1250
Fountain1152
Blackford1142
Pulaski1131
Crawford1020
Brown1013
Parke932
Benton880
Union770
Ohio767
Switzerland680
Warren401
Unassigned0225

COVID-19 Important links and resources

As the spread of COVID-19, or as it's more commonly known as the coronavirus continues, this page will serve as your one-stop for the resources you need to stay informed and to keep you and your family safe. CLICK HERE

Closings related to the prevention of the COVID-19 can be found on our Closings page.

Community Events