Purdue Center for Cancer Research begins using Tyler Trent's donated cells for research

The Purdue Center for Cancer Research has launched a new research program that uses Tyler Trent's cancer cells. Prior to his death on Jan. 1, Tyler donated his osteosarcoma tumors.

Posted: May 14, 2019 5:23 PM
Updated: May 15, 2019 11:32 PM

WEST LAFAYETTE, Ind. (WLFI) - The Purdue Center for Cancer Research has launched a new research program that uses Tyler Trent's cancer cells. Prior to his death on Jan. 1, Tyler donated his osteosarcoma tumors.

The initiative, announced Tuesday, is a collaborative effort between Dr. David Nolte and Dr. John Turek. The two will work together to develop a process that measures cell motion, according to the Purdue Center for Cancer Research. When cells in biop­sies or tissue collected during surgery is exposed to chemotherapy agents, active agents induce different cell motion than inactive agents. The process, called Biodynamic Imaging, will be used in along with doctors from Riley Children's Hospital to identify osteosarcoma chemo sensitivity. 

Although he's been in the field for many years, this process is different for researcher John Turek.

"We've looked at many many tissues from patients but never before have I known the name or actually anything about the patient," said Turek. 

Researchers will work to understand how Tyler's tissue responds to various drugs. Turek said that's important because genetic information isn't helpful in most pediatric cancers.

"It will actually allow us to link a lot of that information back to genetic information and other information that they have on these tumors and that will allow us to begin to design clinical trials and research that will benefit future patients."

Purdue Center For Cancer Research's Director Timothy Ratliff said research like this comes at an especially important time.

"We've got probably 11 drugs in clinical trials right now, some are in the last stage before FDA approval, we're making a whole lot more and with Tyler's help we're going to really discover some cures for that osteosarcoma."

Tyler was a student member of the Purdue Center For Cancer Research's Director's Advancement Board. Tyler died on New Year's Day after his battle with Osteosarcoma, a rare form of bone cancer. He captivated the hearts of the world for his positive spirit and platform to fight the disease.

The center also announced two other collaborative research initiatives to honor Tyler's legacy.

The Purdue Center for Cancer Research said Dr. Philip Low has developed new technology that allows Chimeric Antigen Receptor (CAR) T cells to be collected from the patient. Then, it can be modified and injected back so their own CAR T cells can target and destroy the cancer cells. This technology is set to go to trial this summer, according to PCCR. 

Dr. Nolte, Dr. Turek and Dr. Micheal Childress are also working with the Biodynamic Imaging to identify chemosensitivity in canine osteosarcoma. The disease is similar to the human version, so it can be tested with the same chemotherapeutic agents in which will help better define the model for future studies. Because of Purdue's Veterinary Clinic and teaching college, the PUCC canine oncology doctors are able work with canine cancers as they present in the clinic.

You can give to the Tyler Trent Research Endowment here. 

 

West Lafayette
Clear
73° wxIcon
Hi: 93° Lo: 72°
Feels Like: 73°
Kokomo
Clear
70° wxIcon
Hi: 91° Lo: 71°
Feels Like: 70°
Rensselaer
Clear
70° wxIcon
Hi: 90° Lo: 70°
Feels Like: 70°
Fowler
Clear
70° wxIcon
Hi: 90° Lo: 70°
Feels Like: 70°
Williamsport
Clear
71° wxIcon
Hi: 92° Lo: 71°
Feels Like: 71°
Crawfordsville
Clear
69° wxIcon
Hi: 91° Lo: 72°
Feels Like: 69°
Frankfort
Broken Clouds
72° wxIcon
Hi: 91° Lo: 72°
Feels Like: 72°
Delphi
Clear
73° wxIcon
Hi: 92° Lo: 71°
Feels Like: 73°
Monticello
Clear
73° wxIcon
Hi: 91° Lo: 70°
Feels Like: 73°
Logansport
Overcast
72° wxIcon
Hi: 92° Lo: 70°
Feels Like: 72°
WLFI Radar
WLFI Temps
WLFI Planner

Indiana Coronavirus Cases

Data is updated nightly.

Confirmed Cases: 48626

Reported Deaths: 2717
CountyConfirmedDeaths
Marion11723689
Lake5212244
Elkhart332051
Allen2815132
St. Joseph198168
Cass16399
Hamilton1596101
Hendricks1414100
Johnson1288117
Porter73637
Tippecanoe7279
Madison66364
Clark66044
Bartholomew58944
Howard58057
LaPorte57926
Vanderburgh5706
Kosciusko5564
Marshall4926
Noble48428
Jackson4723
LaGrange4719
Delaware45050
Boone44943
Hancock44935
Shelby43025
Floyd38244
Morgan32931
Monroe30128
Montgomery29720
Grant29526
Clinton2892
Dubois2836
Henry28016
White26510
Decatur25532
Lawrence24625
Vigo2368
Dearborn23323
Warrick22129
Harrison21622
Greene19032
Miami1842
Jennings17612
Putnam1708
DeKalb1634
Scott1628
Daviess14717
Wayne1426
Orange13523
Perry1359
Steuben1302
Franklin1268
Ripley1227
Jasper1212
Wabash1132
Carroll1102
Fayette1017
Newton9910
Whitley965
Starke933
Gibson872
Randolph804
Huntington782
Wells751
Jefferson722
Fulton711
Jay680
Washington671
Pulaski661
Knox640
Clay604
Rush583
Adams501
Owen491
Benton480
Sullivan451
Posey440
Spencer411
Blackford392
Brown391
Crawford320
Fountain322
Tipton311
Switzerland270
Martin230
Parke230
Ohio170
Vermillion140
Warren141
Union130
Pike110
Unassigned0193

COVID-19 Important links and resources

As the spread of COVID-19, or as it's more commonly known as the coronavirus continues, this page will serve as your one-stop for the resources you need to stay informed and to keep you and your family safe. CLICK HERE

Closings related to the prevention of the COVID-19 can be found on our Closings page.

Community Events