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Pfizer CEO says company on track to manufacture 1.3 billion Covid-19 vaccine doses globally next year

At Pfizer's facility in Michigan, the coronavirus vaccine has been loaded onto trucks and airplanes and shipped out for distribution across the US. CNN's Pete Muntean reports.

Posted: Dec 14, 2020 10:51 AM
Updated: Dec 14, 2020 10:51 AM

With about 50 million doses of the Pfizer/BioNTech Covid-19 vaccine coming this year and about 1.3 billion slated to be manufactured next year, Pfizer is working to meet US demands for more doses, company CEO Albert Bourla said Monday.

His interview comes after a weekend in which the vaccine cleared its final hurdle for US emergency use -- being approved for people 16 and older -- and as hundreds of thousands of vials are loaded on trucks for delivery to all 50 states.

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Dr. Robert Redfield, director of the US Centers for Disease Control and Prevention, and Dr. Stephen Hahn, commissioner of the US Food and Drug Administration, have expressed hope that the immunizations begin Monday, as soon as the vials land in health care workers' hands. Several state officials have indicated vaccinations will begin Monday.

Bourla's remarks also come as the US is expected to soon see its coronavirus death toll hit 300,000.

No deal for US second quarter yet

The 50 million doses scheduled for distribution this year have already been manufactured, the CEO said, and half will go to the United States, while the other 25 million will go to the rest of the world.

Next year, Bourla expects US and European manufacturers to create another 1.3 billion doses. Pfizer and its partner, BioNTech, are maxing out capacity on both sides of the Atlantic, he said.

Of those, about 100 milliion will go to the States in the first quarter of 2021, per an agreement between the government and the vaccine makers, and 1.2 billion will be sent to other countries, he said.

The US government would like another 100 million doses in the second quarter, but as of right now, there is no deal in place and Bourla sees the third quarter of 2021 being a more realistic target.

"We are working very collaboratively with them to make sure that we can find ways to produce more or allocate the doses in the second quarter as well, but we haven't signed this agreement yet," he told CNN.

Freight trucks carrying almost 1 million doses of the vaccine left or were scheduled to leave Pfizer's Portage, Michigan, plant Sunday, with close to 2 million more doses expected to leave Monday for a Tuesday arrival. A CNN crew saw action on the docks of the Portage plant Monday, and trucks were expected to begin rolling out in the morning.

Pfizer/BioNTech's vaccine won't likely be the only option. An FDA committee is reviewing a vaccine from Moderna, which is similar to Pfizer/BioNTech's, and will discuss its emergency use authorization this week. US Health and Human Services Secretary Alex Azar, in a Monday interview with NBC, also raised the prospect of Johnson & Johnson's and AstraZeneca's vaccines getting approval next month.

Scale no concern, but there may be 'bumps'

Asked if scale was a concern -- if there might be issues with raw ingredients, manufacturing limitations or quality control -- Bourla said there are rules demanding the highest standards of quality, and while he was concerned earlier in the process, there are "fewer worries now because already we know how to do it."

"Although it looks like a giant step, for us it's what we do every day, so right now I feel quite comfortable that we will be able to do it smoothly," he said. "I'm sure that there will be bumps across the way, but also I'm certain that this is normal life for us and we will be dealing with them and we will deliver these quantities."

The vaccine will require two injections, the second dose coming 21 days after the first. While FDA briefing documents show a 52.4% efficacy after a lone dose, Bourla said American health officials are aware of the expected impact after one dose yet maintain that people should receive the second dose. Efficacy after two doses soars to 95%.

"This was something that the both FDA and CDC considered a lot and they arrived, I think, at recommending you should complete the second dose," he said.

It's expected that of the first 6 million doses scheduled for American distribution, about half will remain in freezers to administer the second doses to those who receive the vaccine first.

Bourla has not received the vaccine yet, he said. An ethical committee is determining who gets the first doses, he said, and he does not want to cut in line. However, he expects to take it soon.

"I think this committee recommends that I will get vaccinated because polls that we have seen said that people will believe much more in this vaccine if the CEO is getting vaccinated so likely I will get it," he told CNN.

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Indiana Coronavirus Cases

Data is updated nightly.

Cases: 660942

Reported Deaths: 12556
CountyCasesDeaths
Marion905601638
Lake48352874
Allen35762635
Hamilton32026396
St. Joseph29865511
Elkhart25350414
Vanderburgh21225377
Tippecanoe19977200
Johnson16319356
Porter15938269
Hendricks15801300
Clark11928180
Madison11730316
Vigo11578229
Monroe10312161
Delaware9830179
LaPorte9755196
Howard9047196
Kosciusko8549109
Bartholomew7440147
Warrick7403150
Hancock7394130
Floyd7189169
Wayne6630191
Grant6422157
Morgan6075125
Boone607288
Dubois5895111
Dearborn546866
Cass543399
Henry541793
Marshall5417104
Noble508578
Jackson464366
Shelby460190
Lawrence4179111
Gibson400881
Harrison398763
Clinton395053
Montgomery386283
DeKalb384678
Miami356763
Knox356485
Whitley348936
Huntington342376
Steuben337855
Wabash330876
Putnam329459
Ripley326861
Adams322549
Jasper315443
White297252
Jefferson294473
Daviess285396
Fayette271456
Decatur270488
Greene261280
Posey260531
Wells257674
Scott249950
Clay240844
LaGrange240770
Randolph225576
Spencer217030
Jennings214744
Washington210427
Sullivan203139
Fountain201142
Starke187951
Owen181953
Fulton178237
Jay177628
Carroll176418
Perry173235
Orange171150
Rush164322
Vermillion160242
Franklin159335
Tipton146141
Parke138815
Pike127432
Blackford120627
Pulaski106444
Newton96531
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Benton91813
Crawford90313
Martin80014
Warren75513
Switzerland7537
Union67110
Ohio53211
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